Detalhe da pesquisa
1.
Hereditary Alpha Tryptasemia: Validation of a Single-Well Multiplex Digital Droplet PCR Assay in a Cohort of Symptomatic Patients.
Clin Chem
; 70(2): 425-433, 2024 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38073287
2.
Dietary methionine starvation impairs acute myeloid leukemia progression.
Blood
; 140(19): 2037-2052, 2022 11 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35984907
3.
Autophagy Proteins ATG5 and ATG7 Are Essential for the Maintenance of Human CD34(+) Hematopoietic Stem-Progenitor Cells.
Stem Cells
; 34(6): 1651-63, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26930546
4.
The nonessential amino acid cysteine is required to prevent ferroptosis in acute myeloid leukemia.
Blood Adv
; 8(1): 56-69, 2024 01 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37906522
5.
Identification of HIF2alpha as an important STAT5 target gene in human hematopoietic stem cells.
Blood
; 117(12): 3320-30, 2011 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-21263150
6.
Tight control of STAT5 activity determines human CD34-derived interstitial dendritic cell and langerhans cell development.
J Immunol
; 186(12): 7016-24, 2011 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21602494
7.
Down-regulation of GATA1 uncouples STAT5-induced erythroid differentiation from stem/progenitor cell proliferation.
Blood
; 115(22): 4367-76, 2010 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-20339093
8.
Presence of mutant p53 increases stem cell frequency and is associated with reduced binding to classic TP53 binding sites in cell lines and primary AMLs.
Exp Hematol
; 110: 39-46, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35315319
9.
Inhibition of the succinyl dehydrogenase complex in acute myeloid leukemia leads to a lactate-fuelled respiratory metabolic vulnerability.
Nat Commun
; 13(1): 2013, 2022 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35440568
10.
The Glycolytic Gatekeeper PDK1 defines different metabolic states between genetically distinct subtypes of human acute myeloid leukemia.
Nat Commun
; 13(1): 1105, 2022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35232995
11.
HIF1/2-exerted control over glycolytic gene expression is not functionally relevant for glycolysis in human leukemic stem/progenitor cells.
Cancer Metab
; 7: 11, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31890203
12.
Chromatin-Based Classification of Genetically Heterogeneous AMLs into Two Distinct Subtypes with Diverse Stemness Phenotypes.
Cell Rep
; 26(4): 1059-1069.e6, 2019 01 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30673601
13.
Inhibition of the transforming growth factor beta (TGFbeta) pathway by interleukin-1beta is mediated through TGFbeta-activated kinase 1 phosphorylation of SMAD3.
Mol Biol Cell
; 16(8): 3501-10, 2005 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-15917296
14.
Multi-omics profiling reveals a distinctive epigenome signature for high-risk acute promyelocytic leukemia.
Oncotarget
; 9(39): 25647-25660, 2018 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29876014
15.
Combined HAT/EZH2 modulation leads to cancer-selective cell death.
Oncotarget
; 9(39): 25630-25646, 2018 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29876013
16.
Inhibition of autophagy as a treatment strategy for p53 wild-type acute myeloid leukemia.
Cell Death Dis
; 8(7): e2927, 2017 07 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-28703806
17.
Oncogenic Ras blocks transforming growth factor-beta-induced cell-cycle arrest by degradation of p27 through a MEK/Erk/SKP2-dependent pathway.
Exp Hematol
; 33(7): 747-57, 2005 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-15963850
18.
Hypoxia-Like Signatures Induced by BCR-ABL Potentially Alter the Glutamine Uptake for Maintaining Oxidative Phosphorylation.
PLoS One
; 11(4): e0153226, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27055152
19.
The Hematopoietic Transcription Factors RUNX1 and ERG Prevent AML1-ETO Oncogene Overexpression and Onset of the Apoptosis Program in t(8;21) AMLs.
Cell Rep
; 17(8): 2087-2100, 2016 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27851970
20.
Erythropoietin-induced serine 727 phosphorylation of STAT3 in erythroid cells is mediated by a MEK-, ERK-, and MSK1-dependent pathway.
Exp Hematol
; 31(5): 398-405, 2003 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-12763138